Read about mononucleosis medical facts: what is the definition of mononucleosis, what are the signs and symptoms, medical treatment & how to treat mononucleosis, information about the causes, diagnosis, and related mononucleosis diseases.

Definition: What is "mononucleosis"?


Infectious mononucleosis (mono), or glandular fever, is often called the kissing disease. The virus that causes this disease is transmitted by saliva, so kissing can spread the virus, but so can coughing, sneezing, or sharing a glass or food utensil. The name comes because the number of mononuclear leukocytes (white blood cells with a one-lobed nucleus) rises importantly.

Symptoms & Signs

Signs & symptoms of mononucleosis may include: Fatigue, Weakness, Sore throat, perhaps a strep throat that does not get better with antibiotics, Fever, Swollen lymph nodes in your neck & armpits, Swollen tonsils, Headache, Skin rash, Loss of appetite, Soft, swollen spleen, Night sweats.

Treatment: How to Treat "mononucleosis"?

There is no specific therapy available to treat infectious mononucleosis. Antibiotics do not work against viral infections such as mono. Treatment primarily involves bed rest & adequate fluid intake.


There are two viruses can cause mononucleosis (mono): the Epstein-Barr virus (EBV) & cytomegalovirus (CMV). Both viruses are part of the herpes family, whose other members include the viruses in charge for cold sores & chickenpox.


Monospot test may be done to check your blood for antibodies to the Epstein-Barr virus. This screening test provides results within a day. But it could not detect the infection during the first week of the illness.

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