Read about lupus medical facts: what is the definition of lupus, what are the signs and symptoms, medical treatment & how to treat lupus, information about the causes, diagnosis, and related lupus diseases.

Definition: What is "lupus"?


Lupus is a chronic inflammatory disease that occurs when your body's immune system attacks your own tissues & organs. Inflammation caused by lupus may affect many different body systems, including your joints, skin, kidneys, blood cells, heart & lungs.

Symptoms & Signs

The signs & symptoms of lupus that you experience will depend on which body systems are affected by the disease. But, in general, lupus signs & symptoms may include: Fatigue, Fever, Weight loss or gain, Joint pain, stiffness & swelling. Butterfly-shaped rash (malar rash) on the face that covers the cheeks & bridge of the nose.

Treatment: How to Treat "lupus"?

Treatment for lupus depends on your signs & symptoms. Recognizing whether your signs & symptoms should be treated & what medications to use requires a careful discussion of the benefits & risks with your doctor. As the signs & symptoms flare & subside, you & your doctor may find that you'll need to change medications or dosages.


Lupus is an autoimmune disease, which means that instead of just attacking foreign substances, such as bacteria & viruses, your immune system also turns against healthy tissue. This leads to inflammation & damage to different parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels & brain.


Diagnosing lupus is difficult because signs & symptoms vary considerably from person to person. Signs & symptoms of lupus can change over time & overlap with those of many other disorders.

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