APUDOMA: WHAT IS APUDOMA?

SIGNS SYMPTOMS / DISEASES INDEX (A) / APUDOMA: WHAT IS APUDOMA?
Read about apudoma medical facts: what is the definition of apudoma, clinical features, and related apudoma diseases.

Definition: What is "apudoma"?

APUDOMA

An apudoma is any endocrine tumor that arises from an APUD cell (APUD, meaning amine precursor uptake & decarboxylation) properties. These cells, which are derived from neural crest cells, are from structures such as the prostate, pancreas & ampulla of Vater. First identified in 1975, Apudoma is a very general term. As such, most doctors & scientists prefer to use a more specific term when possible, such as apudoma of gall bladder.

Clinical Features

"Structurally, apudoma tumors often display electron-dense granules, which produce multiple regulatory amines & hormones, chromogranin A or C, synaptophysine & neuron-specific enolase. Amine precursor uptake & decarboxylation cells are known to give rise to islet cell tumors of the pancreas, medullary carcinomas of the thyroid, phaeochromocytomas, melanomas & carcinoid tumors. As such, symptoms & histology of pancreatic islet cell tumors & apudoma have striking similarities. "



Share on Google Plus Share on Facebook Share on Twitter Share on LinkedIn

Home | About | Contact | Privacy Policy | Sitemap
Copyright 2018 © SignsSymptoms.org - All Rights Reserved