ARAKAWA'S SYNDROME II: WHAT IS ARAKAWA'S SYNDROME II?
Definition: What is "Arakawa's syndrome II"?
Arakawa's syndrome ii definition: An error of metabolism that is inherent is known as Arakawa's syndrome II. A hereditary disorder caused by the absence of the enzyme tetrahydrofolate-methyltransferase. People who has this disease cannot properly digest methylcobalamin a kind of Vitamin B12. Other terms for this disease are Methionine synthase deficiency, N5-methylhomocysteine transferase deficiency & Tetrahydrofolate-methyltransferase deficiency syndrome.
Symptoms & Signs
Here is a list of the known symptoms of Arakawa's Syndrome II: Megaloblastic anemia - reduced production of red blood because of the lack of vitamin B12 absorption, a rare blood disorder. Delay in physical & mental development Deficit in Methionine synthase Scoliosis - a state that presents lateral curvature of the spine. Retarded growth - growth rate is not enough for the normal rate. Fragile muscle tone liver is bloated spleen is bloated Seizures - unrestrained physical movements. Complications of Arakawa's syndrome II Production of red cell is reduced Learning disability - several developmental troubles hindering learning. Macrocytosis (erythrocyte) - unusual large red blood cell taking place primarily in anemias also referred to as megalocyte.
According to Office of Rare Diseases (ORD) of the National Institutes of Health (NIH) Arakawa's syndrome is listed as a "rare disorder" which indicates that it affects less than 200,000 people in the US.