Read about angular cheilitis medical facts: what is the definition of angular cheilitis, what are the signs and symptoms, medical treatment & how to treat angular cheilitis, information about the causes, diagnosis, and related angular cheilitis diseases.

Definition: What is "Angular Cheilitis"?


Angular cheilitis definition: A chronic inflammatory condition of the corners of the mouth is called angular cheilitis or perleche. It is usually associated with a bacterial (Staphylococcal) or fungal (Candidal) infection & those infected may also have thrush (an oral candidiasis). Depending upon whether or not the affected person seeks treatment, the condition can last from days to months.

Symptoms & Signs

Found in the corners of the mouth, a patient with angular cheilitis may notice ulceration, tissue softness & tenderness, cracking & fissuring of the corners of the mouth, with redness & as well as drainage of pus.

Treatment: How to Treat "Angular Cheilitis"?

Clotrimazole, nystatin & econazole are topical antifungals which are usually undertaken for the treatment of angular cheilitis. What may also be prescribed are combinations of a topical antifungal & a topical steroid such as mycostatin, hydrocortisone & triamcinolone or iodoquinol.


Among the variety of reasons why angular cheilitis occurs are from bacterial (Staphylococcal) or viral infections & as well as fungal (Candidiasis) or yeast infection. Those who are taking the isotretinoin medication for acne are more vulnerable to angular cheilitis caused by bacterial & fungal infections. Dentures that are worn & do not fit properly can also be a cause for angular cheilitis because of the friction & folds being created. Deficiencies in vitamin B-2 (riboflavin), B-3 (niacin), vitamin B-6 (pyridoxine), vitamin B-12 (cyanocobalamin) & a defieciency in iron are also among the causes of angular cheilitis.


A dentist or a doctor can diagnose angular cheilitis in different ways, depending on what causes the disease. The problem can also be diagnosed by your dentist by judging the fit of your dentures.

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