ALBRIGHT'S SYNDROME & TREATMENT
Definition: What is "Albright's syndrome"?
Albright's syndrome definition: In 1937, Donovan James McCune & Fuller Albright explained Albright's syndrome as an inherited condition distinguished by abnormalities in the skin pigmentation, bone ailments & endocrine complications. The diseases in the bone may result to the weakness of the bone & abnormalities in the legs, arms & skull. Diseases in the endocrine may the reason for early puberty & elevated growth rate. Patients are affected by several distinctiveness of the ailment to various degrees several individuals may have the condition & have no evident complications.
Symptoms & Signs
It is supposed that when two of the three subsequent features are evident: (autonomous) endocrine hyperfunction such as precocious puberty Fibrous dysplasia CafΘ-au-lait spots
Treatment: How to Treat "Albright's syndrome"?
1) Bone treatments a) Surgical bone grafting b) Surgical bone pinning c) Surgical bone casting 2) Ovary surgery a) Surgical ovary cyst removal b) Ovary removal 3) Estrogen inhibitors a) Testolactone - artificial androgen with antineoplastic movement. Prevents the development of estrogen from adrenal androstenedione & reducing endogenous estrogen levels because it inhibits steroid aromatase. b) Fadrozole 4) Thyroid-inhibiting medications a) Propylthiouracil b) Methimazole 5) Pituitary-related treatments a) Pituitary surgery b) Somatostatin medications 6) Treatments for phosphorus problems a) Oral phosphates b) Vitamin D
LH blood test FSH blood test Phosphate urine test Ultrasonography X-ray - for bone disease