Read about agyria medical facts: what is the definition of agyria, what are the signs and symptoms, medical treatment & how to treat agyria, information about the causes, and related agyria diseases.

Definition: What is "Agyria"?


Agyria which actually means smooth brain is an unusual brain formation disorder distinguished by the absence of normal folds in the brain. Malfunctioning neuronal movement is the cause of Agyria where in the nerve cells travel from their original place to their stable location. It is a kind of cephalic disorder. Convolutions or gyri refer to the folds in the brain & this forms the surface of the normal brain. Young patients who have Agyria has have a lack of or partially formed convolutions which makes the exterior of the brain smooth.

Symptoms & Signs

The symptoms seen in a patient with Agyria includes: abnormal facial look, trouble swallowing, failure to thrive & rigorous psychomotor retardation. Abnormalities of the hands, fingers, or toes, muscle spasms & fits may also happen.

Treatment: How to Treat "Agyria"?

The treatment for Agyria is symptomatic & is based upon the severity & locations of the brain abnormalities. Patient must be provided with supportive care which will help in to comfort the patient & aids in nursing needs. Medications may control fits & shunting may be needed for hydrocephalus. Gastrostomy may be needed when the patient has difficulty in eating. The degree of brain abnormality is the basis for the prognosis of children which can vary. Beyond a 3- to 5- month-old level, several persons present no major development. Others may have normal growth or intelligence. Before the age of 2 several patients will die though because of modern medications & care patients can live until they are teenagers. The most usual reason of death is respiratory complications.


The list below shows the probable medical causes of Agyria: Norman-Roberts syndrome Walker-Warburg syndrome Cytomegalovirus, congenital Lennox-Gastaut syndrome Muscle-eye-brain disease Fukuyama congenital muscular dystrophy Congenital muscular dystrophy, autosomal recessive Miller-Dieker syndrome

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