ADRENAL HYPERPLASIA & TREATMENT
Definition: What is "Adrenal hyperplasia"?
Congenital adrenal hyperplasia (CAH) generally refers to several autosomal recessive medical conditions that are results from some biochemical pathway of the steroidogenesis of the cortisol from cholesterol by the patient's adrenal glands. Majority of these conditions involve lesser or greater production of sex steroids & can also greatly alter the development of primary & secondary sex characteristics in affected individuals.
Symptoms & Signs
Patients displaying non-sever symptoms include normal genitalia at birth, although clitoromegaly & pubic hair tend to appear in early childhood. Other indicators include high blood pressure & hypokalemia.
Treatment: How to Treat "Adrenal hyperplasia"?
For infants born with ambiguous genitalia are required to be closely observed for any symptoms of salt wasting while a diagnosis is being established. For patients suffering from dehydration & hyponatremia should receive intravenous fluid containing isotonic sodium chloride
The particular defects that cause the congenital adrenal hyperplasia include the autosomal recessive disorders that may be due to deficient activity of a protein that is involved in cortisol & aldosterone. In majority of the cases, CAH is mainly due to a deletion or mutation of the particular gene that codes for the protein.
Among the most prominent clinical clues include the patient's abnormal weight loss & signs of electrolyte abnormalities