Read about adie syndrome medical facts: what is the definition of adie syndrome, what are the signs and symptoms, medical treatment & how to treat adie syndrome, information about the causes, diagnosis, and related adie syndrome diseases.

Definition: What is "Adie syndrome"?


Adie syndrome, sometimes reffered to as Adie's Tonic Pupil or Holmes-Adies Syndrome is categorized as a neurological disorder that affects the autonomic nervous system & the pupil of the patient's eye. It causes damage to the postganglionic fibers of the eye that is usually brought about by bacterial or viral infection.

Symptoms & Signs

There are three common symptoms of Adie syndrome: losss of deep tendon reflexes, diaphoresis & abnormal pupil size. Other usual indicators include hyperopis, difficulty in reading & photophobia.

Treatment: How to Treat "Adie syndrome"?

The most common treatment of Adie syndrome include a prescription of reading glasses to effectively correct the patient's impairment. Also, pilocarpine drops can be administered as a diagnostic measure, usually applied three times a day. In cases where the condition is not treatable by drug therapy, thoracic sympathectomy is known to be the definitive treatment.


The most common cause of Adie syndrome is viral infection. Tumors, vascular lesions, trauma, giant cell arteritis & diabetes can also inflict serious damage on the ciliary ganglion.


The patient's clinical examination may reveal some sectoral paresis of the iris. In some cases, the tonic pupil appears smaller over time. CT & MRI scanning can also significantly help in the diagnostic testing of the patient's focal hypoactive reflexes.

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