ACUTE INTERMITTENT PORPHYRIA & TREATMENT
Definition: What is "Acute intermittent porphyria"?
Acute intermittent porphyria is a very rare metabolic disorder that is characterized by an abnormal deficiency of porphobilinogen deaminase enzyme that would result to the buildup of polyphyrins. This medical condition is inherited & is passed on from one generation to another.
Symptoms & Signs
For patients who inherited & are suffering from AIP, most symptoms usually manifest right after puberty, especially among women who undergo hormonal influences. These symptoms occur as attacks that can go on for hours & possibly stretch for several days. Indicators include severe abdominal pain, vomiting, constipation nausea, urinary retention, palpitation, seizures & hallucinations. Patient may also feel pain around the arms, legs & beck area & well as general muscle weakness.
Treatment: How to Treat "Acute intermittent porphyria"?
Attacks of acute intermittent porphyria can be best deflected through the diligent maintenance of the patient's nutrition as well as the avoidance of medications that may trigger the disorder. Heme is also administered to prevent any attacks.
Acute intermittent porphyria is acquired through the genes. Studies have shown that this medical condition is remarkably more prevalent in Northern Europe & are known to be more common among women.
To properly diagnose this disease, several laboratory tests on the patient's urine sample needs to be performed to determine any increase of the heme precursors. Relative of the patient who does not display any symptom can still be identified as carriers through the measurement of the red blood cells & undergoing DNA testing.