Read about apocrine duct occlusion medical facts: what is the definition of apocrine duct occlusion, what are the signs and symptoms, medical treatment & how to treat apocrine duct occlusion, information about the causes, diagnosis, and related apocrine duct occlusion diseases.

Definition: What is "Apocrine Duct Occlusion"?


Apocrine duct Occlusion, commonly known as the Fox-Fordyce disease, is an uncommon skin disorder, affecting male & children, but is more common in women between 13 & 35 years old. This condition is characterized by the sudden development of itchy bumps usually around hair follicles of nipples, underarm areas & pubic region.

Symptoms & Signs

Apocrine duct Occlusion starts with an intense itchy that could disrupt sleep. However, some cases are asymptomatic. Common signs include a darkened & thickened dry skin due to persistent scratching, dome-shaped small papules that affect hair follicles in the infected area & an obvious reduce in sweating in the affected area.

Treatment: How to Treat "Apocrine Duct Occlusion"?

There is no specific cure for Apocrine duct occlusion. However, oral antibiotics, topical steroids, topical retinoids & clindamycin solution may be prescribed to help alleviate the itchiness. Other therapies may include surgical excision, ultraviolet radiation, dermabrasion, liposuction & anti-androgenic hormonal therapy. Some cases clear up during pregnancy or menopause for unknown reasons. However, the disease could persist afterwards.


The cause of Apocrine duct Occlusion remains unknown. However, it has been associated with rupture of the apocrine sweat ducts, which result in the inflammation & itching of the affected area. Other factors that may play a role in the development of this condition include stress, changes in sweat components, emotional & hormonal influences as well as environmental factors, like humidity, heat & friction.


Diagnosis is made by observing clinical signs of the rash & assessing patient history.

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