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Read about antitrypsin medical facts: what is the definition of antitrypsin, what are the signs and symptoms, medical treatment & how to treat antitrypsin, information about the causes, diagnosis, and related antitrypsin diseases.

Definition: What is "Antitrypsin"?


Alpha 1-antitrypsin deficiency is a genetic defect caused by an abnormal production of alpha-1 antitrypsin, a protein that thrives in the liver cells. The lack of this protein may cause severe disorders in the different organs & weakness of the immune system.

Symptoms & Signs

People with alpha-1 antitrypsin deficiency suffer from shortness of breath, rales & ronchi. They are also more prone to emphysema & liver disease.

Treatment: How to Treat "Antitrypsin"?

Treatment of the disorder is done by intravenous infusions of alpha-1 antitrypsin that came from donated plasma. However, this treatment is not recommended to persons suffering from liver disease. Liver transplant may be needed for severe cases.


Apart from being a genetic defect, the disease can also be aggravated by cigarette smoking, since the airways & other respiratory organs need alpha 1-antitrypsin as their protection against the effects of nicotine.


Diagnosis can be done by genetic testing.

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